PhD Scholarship in Bioinformatics with a focus on Pandemics and Zoonoses – DTU Health Tech

Profilbillede
dato

BEMÆRK: Ansøgningsfristen er overskredet

In this position you will work as a bioinformatics researcher, in close collaboration with researchers from diverse fields, on analysing a set of core questions related to understanding pandemics and emerging disease: Which features allow some pathogens to emerge and cause a pandemic? What are the inner workings of the pandemic period in which the pathogen evolves and human immunity builds? What controls a pandemic’s trajectory; e.g., recurrent waves. What is the impact on population health? And lastly, what governs the end of the pandemic period and potential transition to endemic disease?

You will join the ongoing efforts of researchers at the Department of Health Technology (DTU Health Tech), Section for Bioinfomatics and the PandemiX Center of Excellence which is funded by the Danish National Research Foundation (DNRF) and led by professor of epidemiology Lone Simonsen at Roskilde University. The position will be both at DTU and at Statens Serum Institut (SSI), where PandemiX has offices.

Responsibilities and qualifications
The main aim of this position will be to apply bioinformatical analysis and modelling to understand zoonotic events at the molecular, organismal, and population scales: While SARS-CoV-2 is the latest virus to cause a pandemic, an enormous number of other viruses lurk at the animal-human interface, well-positioned to make the leap. We aim to understand why zoonotic events occur, including the roles of viral replication and evolution in the host organism, immune-response and evasion, human-animal interaction dynamics, receptor binding and internalization in human cells, and potential for pathogen spread. What molecular signatures are necessary? What determines how likely an animal virus is to jump and evolve in a new host? Can we minimize the risk?

The following requirements must be met by the successful candidate:

  • Strong skills in programming (Python and R) and computing (Linux/UNIX/HPC)
  • Strong skills and experience within the field of bioinformatics
  • Experience working with sequence analysis of large genomic data sets.
  • Experience performing phylogenetic and phylodynamic analyses
  • Experience with methods for virus surveillance 
  • Solid knowledge of basal molecular biology
  • Knowledge of the biology of viruses and other pathogens

Previous publications in the field will be considered an added advantage. The ideal candidate should exhibit the ability to work autonomously and foster collaborations with a broad spectrum of experts from intersecting disciplines.

You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.

Approval and Enrolment  
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU's rules for the PhD education

Assessment
The assessment is made by Professor Anders Gorm Pedersen and Professor Lone Simonsen.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms 
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years. Starting date is 1 January 2024, or as soon as possible thereafter. 

You can read more about career paths at DTU here

Further information  
Further information may be obtained from the principal supervisor Anders Gorm Pedersen (agpe@dtu.dk ), professor of Bioinformatics at DTU. Lone Simonsen, professor of Epidemiology at Roskilde University, will be a co-supervisor of the project.

You can read more about DTU Health Tech and the Section for Bioinformatics at healthtech.dtu.dk/english and www.healthtech.dtu.dk/english/research/research-sections/section-bioinformatics .

You can read more about the PandemiX Center at www.ruc.dk/en/pandemix

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark . Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar ” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU. 

Application procedure 
Your complete online application must be submitted no later than 14 December 2023 (23:59 Danish time) . Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file . The file must include: 

  • A letter motivating the application (cover letter)
  • Curriculum vitae 
  • Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale
  • Publication list (if applicable)

You may apply prior to ob­tai­ning your master's degree but cannot begin before having received it.

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

PandemiX Center of Excellence: The overall research objective of PandemiX is to investigate signature features of pathogens with pandemic potential (including historical outbreaks), to better prepare for future pandemics. We strive to make breakthroughs not hitherto possible or attempted, ranging from a profound understanding of how to control transmission in the short run, to how best to secure robust population immunity in decades to come. The PandemiX Center will give rise to a new field, pandemiology, home to a growing cadre of interdisciplinary researchers ready to address the inevitable next pandemic. The PandemiX partners include labs at Roskilde University (RUC), the Technical University of Denmark (DTU), the Niels Bohr Institute at the University of Copenhagen (UCPH) and North Zealand Hospital (NOH).

DTU Health Tech, Bioinformatics: In the Section for Bioinformatics, we combine knowledge of biology with informatics to study questions that are often relevant to human health but equally often of a fundamental nature. The groups of the Section cover a wide variety of subjects including personalized medicine, immunoinformatics, cancer systems biology, molecular evolution, protein structure and sorting, and single cell omics. Our work is done in close collaboration with research, industrial and medical partners with a focus on keeping our research as relevant as possible.

The work environment at DTU and at the PandemiX Center is very exciting, interdisciplinary and allows fantastic scientific and social interactions with many talented researchers.

DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Tech’s expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 210 persons, 140 PhD students and a technical/administrative support staff of about 160 persons, of which a large majority contributes to our research infrastructure and related commercial activities.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

INFORMATIONER OM STILLINGEN:

- Arbejdspladsen ligger i:

Lyngby-Taarbæk Kommune

-Virksomheden tilbyder:

-Arbejdsgiver:

DTU Space, Ørsteds Plads, 2800 Kongens Lyngby

-Ansøgning:

Ansøgningsfrist: 14-12-2023; - ansøgningsfristen er overskredet

Se mere her: https://job.jobnet.dk/CV/FindWork/Details/5951561

Denne artikel er skrevet af Emilie Bjergegaard og data er automatisk hentet fra eksterne kilder, herunder JobNet.
Kilde: JobNet