BEMÆRK: Ansøgningsfristen er overskredet
If you have a key research interest in development of hydrogels for a clinical relevant purpose, then this might be the right PhD position for you.
The aim of the PhD project is to develop in situ
hydrogels for nasal delivery with the purpose of targeting bacterial biofilm in the sinuses. Your focus will be on i) developing in situ
hydrogels encapsulating antibiotic(s), ii) to in vitro
characterize the developed gels and ensure they can deposit in the sinuses and iii) to explore any toxicological and sensory effects of the hydrogels in vitro
and ex vivo.
The PhD candidate will be a part of the Pharmaceutical Technology group (see more information on the homepage). In the group, we are exploring and developing targeted and advanced drug delivery systems to be able to e.g. deliver vaccines and peptides/proteins by the oral, buccal and nasal routes. The ultimate goals of these activities are to enhance the systemic uptake to prevent and/or cure diseases or to have a targeted release of drug in specific locations in the body. The group is part of the Drug Delivery and Sensing (IDUN) section at DTU Department of Health Technology. The IDUN section is highly cross-disciplinary with more than 40 members focusing on development of micro and nanotechnology based sensors, detection systems and drug delivery systems.
Research field
You will primarily be working on development and testing of in situ
hydrogels. In the development phase, there will be a main focus on polymer selection for the gels and on obtaining a sustained release of the antibiotics from the gels. During development, the gels are characterized for example for its mechanical parameters and viscoelastic behaviours and further, it needs to be tested if there are unwanted toxicological and sensory effects.
The project is part of a Sapere Aude grant from Independent Research Fund Denmark. The project will be carried out in close collaboration with colleagues from the Pharmaceutical Technology group and from the IDUN section.
Responsibilities and qualifications
You will be responsible for material selection, development of the hydrogels for sinus deposition and characterization of the gels.
You are expected to have a background in areas related to pharmaceutical sciences/technology, chemistry or material sciences.
You are highly independent, self-motivated and enjoy collaboration in a multidisciplinary academic environment. You have the ability to drive the project forward and to set and achieve ambitious goals.
You enjoy supervising and teaching BSc and MSc students.
The project is highly interdisciplinary and we expect that you enjoy teamwork and are good at coordinating your work with your colleagues.
You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.
Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU's rules for the PhD education
.
Assessment
The assessment of the applicants will be made by Associate Professor Line Hagner Nielsen.
We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years. The starting date will, at the earliest, be 15 March 2024.
You can read more about career paths at DTU here http://www.dtu.dk/english/about/job-and-career/working-at-dtu/career-paths.
Further information
Further information may be obtained from Associate Professor Line Hagner Nielsen (lihan@dtu.dk
).
You can read more about DTU Health Tech at www.healthtech.dtu.dk/english.
If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark
. Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar
” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU.
Application procedure
Your complete online application must be submitted no later than 31 December 2023 (23:59 Danish time)
. Applications must be submitted as one PDF file
containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file
. The file must include:
- A letter motivating the application (cover letter)
- Curriculum vitae
- Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale
You may apply prior to obtaining your master's degree but cannot begin before having received it.
Applications received after the deadline will not be considered.
All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.
DTU Health Tech
DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Techs expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 210 persons, 140 PhD students and a technical/administrative support staff of about 160 persons, of which a large majority contributes to our research infrastructure and related commercial activities.
Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.
INFORMATIONER OM STILLINGEN:
- Arbejdspladsen ligger i:
Lyngby-Taarbæk Kommune
-Virksomheden tilbyder:
-Arbejdsgiver:
Danmarks Tekniske Universitet, Anker Engelunds Vej, 2800 Kongens Lyngby
-Ansøgning:
Ansøgningsfrist: 31-12-2023; - ansøgningsfristen er overskredet
Se mere her: https://job.jobnet.dk/CV/FindWork/Details/5954163
