BEMÆRK: Ansøgningsfristen er overskredet
The Department of Chemistry at the Technical University of Denmark (DTU) is offering a 3-year PhD scholarship in the field of Physical Chemistry and Bioscience. The project will be carried out as a collaboration between DTU Chemistry, DTU Chemical Engineering, Novozymes A/S, and the Department of Biochemistry and Molecular Biology at Michigan State University.
The main objective of this project is to investigate and understand the behavior of enzymes at gas-liquid interfaces, particularly focusing on bubbles, utilizing advanced computer simulation techniques. In various reactor setups, such as those where substrate gases like oxygen are introduced, enzymes come into direct contact with gas bubbles. When enzymes adhere to such gas-liquid interfaces, it can lead to their unfolding, resulting in a loss of their functional properties.
To address this challenge, we will employ sophisticated computational simulation techniques to explore how enzymes interact with gas-liquid interfaces. This investigation will involve monitoring changes in the structural and dynamic properties of enzymes as they adsorb to bubbles of varying sizes and compositions.
The insights obtained from these simulations will be compared and aligned with experimental data provided by DTU Chemical Engineering. These experiments will be conducted under carefully controlled conditions in a specially designed reactor, enabling us to quantify the amount and size of gas bubbles while preserving enzyme activity and stability.
The ultimate goal of this collaborative effort is to establish strong connections between experimental observations and simulation outcomes. This alignment will be instrumental in developing a novel predictive tool capable of forecasting enzyme activity maintenance under specific conditions.
During the PhD program, the candidate will spend approximately six months at the Department of Biochemistry and Molecular Biology, Michigan State University, USA, taking advantage of their specialized knowledge in coarse-grained simulation techniques and interactions of biomolecules with phase boundaries.
The project will be closely monitored and supported by Novozymes, who will actively participate in regular meetings and share their valuable industrial expertise.
Required qualifications
Applicants should hold a Master of Science degree in Chemistry, Computational Science, or a master’s degree that provides a strong basis of simulation techniques.
Moreover, the candidate should have:
- Prior experience with simulation techniques.
- Comprehension of protein structure and function.
- Proficiency in English and communication skills.
- Desire to be a part of a multidisciplinary environment.
It is not essential that the candidate has experimental skills, as the experimental part of the project will be carried out by DTU Chemical Engineering.
You must have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.
Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see DTU's rules for the PhD education
.
Assessment
The scholarships for the PhD degree are subject to academic approval, and the candidates will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide.
We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.
You can read more aboutcareer paths at DTU here http://www.dtu.dk/english/about/job-and-career/working-at-dtu/career-paths.
Further information
For further information, please contact Professor Günther H.J. Peters (e-mail: ghp@kemi.dtu.dk) or Professor John M. Woodley (e-mail: jw@kt.dtu.dk).
You can read more about us at https://www.kemi.dtu.dk/ and https://www.kt.dtu.dk/ .
If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark . Furthermore, you have the option of joining our monthly free seminar “PhD relocation to Denmark and startup “Zoom” seminar ” for all questions regarding the practical matters of moving to Denmark and working as a PhD at DTU.
Application procedure
Your complete online application must be submitted no later than 2 January 2024 (23:59 Danish time)
. Applications will be evaluated continuously.
Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file . The file must include:
- A letter motivating the application (cover letter)
- Curriculum vitae
- Grade transcripts and BSc/MSc diploma (in English) including official description of grading scale
You may apply prior to obtaining your master's degree but cannot begin before having received it.
Applications received after the deadline will not be considered.
All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.
Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.
INFORMATIONER OM STILLINGEN:
- Arbejdspladsen ligger i:
Lyngby-Taarbæk Kommune
-Virksomheden tilbyder:
-Arbejdsgiver:
Danmarks Tekniske Universitet, Anker Engelunds Vej, 2800 Kongens Lyngby
-Ansøgning:
Ansøgningsfrist: 02-01-2024; - ansøgningsfristen er overskredet
Se mere her: https://job.jobnet.dk/CV/FindWork/Details/5954070
